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Vitamin B12 is good for you. But many people don’t get sufficient B12 from their diets alone. Reasons range from age-related insufficiency to dietary intake: B12 comes primarily from animal sources, so those following a vegetarian diet may not get enough.
Our new B12 Elite combines two types of cobalamin: adenosylcobalamin and methylcobalamin. These are “active” forms—meaning your body can make use of them right away.
Adenosylcobalamin helps preserve neuronal function
Leucine-Rich Repeat Kinase 2 (LRRK2) is a type of enzyme that modifies other proteins by adding phosphate groups.1 Inhibiting the activity of this enzyme has been associated with helping to preserve neuronal tissue.2
A series of preclinical studies has shown that the adenosylcobalamin form of B12 can inhibit the activity of multiple LRRK2 variants in neurons by decreasing phosphorylation (the addition of phosphate groups to amino acids).3
These studies found that adenosylcobalamin helped regulate healthy release of dopamine, a neurotransmitter that plays an important role in cognitive functions such as motor control, arousal, reinforcement and reward.3-6
A cofactor for energy metabolism
Adenosylcobalamin is active in the mitochondria, the powerhouses of your cells. It’s required as a cofactor for the synthesis of succinyl-CoA, a compound that supports cellular energy metabolism.7-9
Methylcobalamin for cellular health & beyond
Methylcobalamin is another neurologically active form of B12 (though in different ways than adenosylcobalamin). Methylcobalamin supports the central nervous system, and it’s essential for the replication and growth of cells.10
Methylcobalamin helps to maintain already healthy homocysteine levels.11-14 Inhibiting excess levels of this compound is key to maintaining healthy cardiovascular and neurological function.
B12 for a healthy brain and more
This B12 formula combines methylcobalamin and adenosylcobalamin to offer optimal cognitive support. Want the health benefits of the full range of the B vitamins? We also offer our BioActive Complete B-Complex formula: a wide-spectrum of B vitamins for whole-body health.
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