S-adenosyl-methionine (SAMe), is made naturally by your body. It participates in many critical metabolic functions by donating methyl groups to other molecules. Methyl groups need to be transferred between compounds in the body to help with things like neurotransmitter signaling and protein function.1,2
Mood, joint & liver health
SAMe helps maintain stable mood3 and joint comfort.4 It also supports liver health, which is not surprising since a large portion of the body's SAMe is made in the liver.5 But SAMe levels decline over time.6
SAMe supports your body's antioxidant defenses by donating sulfur molecules to help with the production of glutathione, one of the body's most important natural antioxidants.7
There is so much research on SAMe that the U.S. Department of Health and Human Services conducted a meticulous evaluation of the evidence. The analysis showed that SAMe has helped maintain stable mood and joint function in several studies.8
Supplementing with SAMe is one way to support the numerous bodily functions that depend on the fascinating biochemical properties of this vital molecule.
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S-adenosyl-methionine, also known as SAMe, is a compound that is responsible for participating in important metabolic functions in the body, including neurotransmitter signaling and protein function. But levels of SAMe decline over time. Supplementing can support joint, liver and mood health.
SAMe has been studied to help maintain a stable mood and emotional well-being.
The majority of the body’s SAMe is produced in the liver, but levels decline over time. Supplementing with SAMe can encourage liver health.
Several studies have shown that supplementing with SAMe helps maintain joint function.
Our formulators hold advanced degrees and use the latest research to decide on the optimal dosages.