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Selenium is an essential micronutrient for human health. In the body, it is incorporated into enzymes and other proteins to make vital compounds known as selenoproteins.1 Perhaps the best-known selenoprotein is the antioxidant enzyme glutathione peroxidase. Each molecule of glutathione peroxidase requires four selenocysteine units and catalyzes a reaction in which a free radical is scavenged by glutathione.2
By balancing cellular oxidation and reduction reactions, glutathione peroxidase and other selenoproteins protect cells and tissues from oxidative damage and support healthy cell function and cell division.1-3
Forms of Selenium
Selenium, as selenocysteine, is also part of an enzyme that helps regulate the activation of thyroid hormone.2 Selenium helps with maintenance of healthy cognition, mood and metabolism by protecting thyroid gland function and optimizing thyroid hormone synthesis and activity.2,4,5
Combining with Vitamins
Maintaining optimal selenium status can help ensure proper regulation of the immune system. In addition to stimulating T cells, natural killer (NK) cells and other immune cells, selenium also supports healthy inflammatory immune activity.6,7 Selenium appears to act synergistically with vitamin E to protect lipids and support immune health.2,8,9 Its absorption and bioavailability are increased in the presence of vitamins A, C, D and E.2
Organic compound
Se-Methyl L-Selenocysteine (MSeC) is a naturally occurring selenium compound that is synthesized by plants such as garlic and broccoli and has demonstrated positive effects on cell function.10 As an organic selenium compound, MSeC is more absorbable than inorganic selenium salts typically used in supplements.2 Unlike selenomethionine, MSeC is closely related to the physiologic form, selenocysteine, needed to synthesize selenoproteins such as glutathione peroxidase.11,12
Actual Size
