Delphinidins
Found in dark red fruits, delphinidins are potent anthocyanin
compounds that activate the production of nitric oxide, supporting
endothelial health, promoting vascular relaxation and helping maintain
already-healthy blood pressure.6-9 Anthocyanins can also help
inhibit inflammatory factors and glycation to support immune health,
protect DNA structure and help maintain healthy blood sugar levels
already within the normal range.10-15 Our formula features delphinidins from maqui berry extract.16
Pyridoxal 5'-phosphate
Glycation is a normal part of the aging process that can affect your health.17-20
To help inhibit glycation, each daily dose of Life Extension Mix™
provides 100 mg of pyridoxal 5'-phosphate, a metabolically active B6
that has been shown to help inhibit glycation reactions.21,22
Standardized pomegranate extract
Our pomegranate extract is standardized to provide punicalagins
specific to this fruit. These potent polyphenols have a wide range of
health benefits: They help maintain blood pressure already within the
normal range, promote healthy endothelial function, inhibit oxidative
stress, positively influence a host of markers for metabolic and
cardiovascular health and promote a healthy inflammatory response.23-34
Blueberry extracts
Life Extension Mix™ features a wild blueberry extract packed with
active blueberry constituents. Blueberry anthocyanins help inhibit free
radicals, while blueberry's other active constituents promote healthy
lipid and glucose levels for those already within the normal range.35,36 Even more exciting: these blueberry constituents may help protect DNA structure and promote healthy cellular proliferation.37-39
In clinical studies, blueberries have been shown to inhibit
inflammatory factors and have antioxidant benefits to support a healthy
immune system and encourage healthy cognitive function.40-43
Standardized green tea extract
Green tea is packed with polyphenol compounds, the most important of
which is epigallocatechin-3-gallate (EGCG). A daily dose of Life
Extension Mix contains 325 mg of a decaffeinated green tea extract
standardized to provide 98% of the active polyphenols that scientists
believe are responsible for green tea's multiple health benefits. Green
tea has been shown to help protect against oxidation, support healthy
cellular proliferation, promote cardiovascular and metabolic health,
maintain healthy DNA structure and protect nerve cells.44-62
Standardized vegetable extracts
Life Extension Mix™ offers a wide array of vegetable extracts,
including a concentrated broccoli mixture with standardized extracts of
sulforaphane and glucosinolates, which are believed to have detoxifying
properties, promote healthy DNA and protect from oxidative stress, among
many other health benefits.63-66
Life Extension Mix™ also contains lutein and lycopene. Lutein, an
antioxidant extracted from marigold and also found in leafy greens such
as kale and spinach, has been shown to help maintain critical pigments
in the macula to support eye health.67 Lycopene from tomatoes helps maintain healthy DNA and cell proliferation and protect against LDL oxidation.68-71
Standardized fruit extracts
In addition to our standardized pomegranate and wild blueberry
extracts, Life Extension Mix™ also features luteolin, a flavonoid shown
to protect against oxidation and help inhibit inflammatory factors to
support immune health.72-74 Our formula also provides fruit
extracts such as bilberry, grape seed and citrus packed with potent
antioxidants to promote visual acuity, a healthy inflammatory response
and healthy blood circulation.75-77
Our proprietary formula is fortified with tart cherry for its
antioxidant benefits for cardiovascular and brain health, as well as
muscle support.78-84 It also includes a customized blend of
blackberry, cranberry, plum, elderberry, persimmon, cherry and other
fruits which studies indicate provide multiple favorable effects on the
body.
Numerous studies have pointed toward the many benefits of olive
polyphenols, and Life Extension Mix™ contains an olive extract
standardized to provide polyphenols like hydroxytyrosol that have been
shown to help inhibit LDL oxidation and protect against oxidative damage
to support cardiovascular health.85,86
Sesame seed lignan extract
Life Extension Mix™ provides 10 mg of a sesame seed lignan extract to
promote healthy levels of gamma tocopherol along with many other
health-promoting properties.87-89 Sesame seed lignans also
protect lipids from oxidation, help support metabolic health, help
maintain already-normal cholesterol/LDL levels and enhance the
beneficial effects of fish oils.90-95
Nutrients to maintain metabolic and cardiovascular health
Life Extension Mix™ contains 500 mcg of Crominex® 3+, the most
advanced chromium complex, as well as highly absorbable forms of
magnesium and biotin to maintain healthy glucose metabolism,
beneficially impact lipid levels and promote cardiovascular health.96-104
High-potency vitamin D3
Evidence shows that many people are not supplementing with enough
vitamin D, a critical nutrient for maintaining strong bone density and
healthy muscle, promoting cardiovascular health and healthy glucose
metabolism, supporting the immune system and more.105-108
Currently, most experts in the field believe that intakes between 1000
and 4000 IU for adults will lead to a healthier blood level of vitamin
D; however, some individuals may require higher doses to achieve a
target blood level of 50-80 ng/mL for 25-hydroxyvitamin D.109
Each daily dose of Life Extension Mix™ provides 2,000 IU of vitamin
D3. What's more, this formula contains only 500 IU of preformed vitamin
A. Preformed vitamin A may interfere with some of the actions of vitamin
D (but this has not been shown to be the case with beta-carotene), yet
most multivitamins contain between 5,000 and 25,000 IU of preformed
vitamin A.
Cyanidin-3-glucoside (C3G)
Life Extension Mix™ contains 1.25 mg of C3G to support eye health.
Found in blackberries and black currants, this potent compound promotes
healthy levels of rhodopsin, a compound that absorbs light in the
retina, and enhances night vision.110
In a clinical study, just 50 mg of a berry extract concentrate
containing C3G helped aging, healthy individuals see better in the
darkness after 30 minutes.111 C3G, which is highly bioavailable, also has potent antioxidant properties and supports endothelial cell health.112-115
5-MTHF (5-methyltetrahydrofolate)
Folate helps maintain homocysteine levels within the normal range,
which is associated with cardiovascular health and supports cognitive
function. One dose of our formula contains 680 mcg DFE of the 5-MTHF
form of folate, which is up to seven times more bioactive than ordinary
folic acid.116
Selenium and Apigenin
Life Extension Mix™ contains three potent forms of selenium
(SelenoExcell®, Se-methyl-selenocysteine and sodium selenite) a trace
mineral with powerful antioxidant properties to support healthy cellular
division, heart and brain health, as well as thyroid function.117,118
Also included is apigenin, a powerful bioflavonoid found in many
vegetables and fruits, with lots of beneficial effects to protect the
body from oxidative damage, promote healthy inflammatory response and
help maintain already-healthy blood pressure and cell division.119-122